Disease Models
Metabolic and Liver Disease Models
GainMed offers unique assays based on its proprietary technologies and access to collections of cells, tissues and other biospecimens to assess certain properties of drug candidates. Data from these models has informed preclinical and clinical development of drugs including drugs that received regulatory approval for their indications.
Metabolic Disease Assays
GainMed ‘s metabolic disease assay programs assess metabolic function and the potential of drug candidates indicated for diabetes and obesity, and include the following assays:
Adipokine Secretion
Fatty Acid and Glycerol Detection
Glucose Uptake
Hepatic Glucose Production
Inhibition of Lipid Accumulation
Lipid Accumulation
Lipolysis
Mitochondrial Mass Assay
Oxygen Consumption Rate Analysis
Pathway Analysis
Liver Disease Models
GainMed’s in vitro liver disease models, developed using its proprietary B-CLEAR® Technology and expertise in bile acid homeostasis, support drug developers in assessing candidates for NAFLD and MASH therapies.